The human brain is the most complex organ in the body. This three-pound mass of gray and white matter sits at the center of all human activity. Not only activities, Your thoughts, your every deed, your existence itself is defined by the brain. The brain makes you conscious. It’s much more complex than what you think. It’s more complex than the universe. Even after years of research neuroscientists feel helpless near the complexity of our brain.


Brain works mysteriously. It works by neurons and their connection, synapse. Every stimulus is a information, there are neurotransmitters which travel inside the neurons. The brain is often likened to an incredibly complex and intricate computer. Instead of electrical circuits on the silicon chips that control our electronic devices, the brain consists of billions of cells, called neurons, which are organized into circuits and networks.

Each neuron acts as a switch controlling the flow of information. If a neuron receives enough signals from other neurons that it is connected to, it fires, sending its own signal on to other neurons in the circuit.To send a message, a neuron releases a neurotransmitter into the gap (or synapse) between it and the next cell. The neurotransmitter crosses the synapse and attaches to receptors on the receiving neuron. The neuronal signal might be excitatory which excites the other neuron. Or it might be inhibitory which inhibits other neurons.


Drugs are molecules which produces effect on the neurotransmission. Some do stimulation of neurons by creating molecules which look like the original molecules. Some exert effect by increasing production of the original molecules. Drugs can alter important brain areas that are necessary for life-sustaining functions and can drive the compulsive drug use that marks addiction. Brain areas affected by drug use include basal ganglia, amygdala prefrontal cortex. It produces motivation, excitation and over activates the reward circuit of brain.


The drugs overstimulate the reward circuit of brain. It makes person euphoric happy. But slowly the area adapts to the drug. The brain becomes dependant on drugs. Without drugs it becomes impossible to be happy. Then brain again gives utter urge to take that medication which the person can’t deny. Without it he/she becomes helpless and sick.

For the brain, the difference between normal rewards and drug rewards can be like the difference between whisper and someone shouting into a microphone. Just as we turn down the volume on a radio that is too loud, the brain of someone who misuses drugs adjusts by producing fewer neurotransmitters in the reward circuit, or by reducing the number of receptors that can receive signals. As a result, the person’s ability to experience pleasure from naturally rewarding activities are reduced.

This is why a person who misuses drugs eventually feels flat, without motivation, lifeless, and/or depressed. Now, the person needs to keep taking drugs to experience even a normal level of reward—which only makes the problem worse, like a vicious cycle.

That’s why for healthy brain say no to drugs. And if someone is taking drugs take them to deaddiction.

Please read and share.


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